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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus

Article Abstract:

A study was conducted to demonstrate that the 1918 virus caused a highly pathogenic respiratory infection in cynomolgus macaque model that culminated in acute respiratory distress and a fatal outcome. The infected animals mounted an immune response characterized by dysregulation of the antiviral response that was insufficient for protection.

Author: Kawaoka, Yoshihiro, Yan Li, Jones, Steven M., Katze, Michael G., Kobasa, Darwyn, Shinya, Kyoko, Halfmann, Peter, Feldmann, Heinz, Kash, John C., Copps, John, Ebihara, Hideki, Hatta, Yasuko, Jin Hyun Kim, Hatta, Masato, Feldmann, Friederike, Alimonti, Judie B., Fernando, Lisa
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
United States, History, Risk factors, Genetic aspects, Respiratory tract infections, Influenza viruses, Influenza Epidemic, 1918-1919

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Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor

Article Abstract:

A study on the brain-derived neurotrophic factor (BDNF) is carried out. The study reports that in cultured cerebellar granule cells, TRPC channels contribute to the brain-derived neurotrophic factor (BDNF)-induced elevation of Ca(super 2+) at the growth cone and are required for BDNF-induced chemo-attractive turnings.

Author: Yan Li, Yi-Chang Jia, Kai Cui, Ning Li, Zai-Yu Zheng, Yi-zheng Wang, Xiao-bing Yuan
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
Brain-derived neurotrophic factor

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Requirement of TRPC channels in netrin-1-induced chemotropic turning of nerve growth cones

Article Abstract:

The existence of transient receptor potential (TRP)-like channel activity is reported in the growth cones of cultured Xenopus neurons. This activity can be modulated by exposure to nextrin-1 and brain-derived neurotrophic factor that are two chemoattractants for axon guidance.

Author: Mu-ming Poo, Gordon X. Wang
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
Xenopus, Neurons

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Subjects list: Research, Cell receptors
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