Derailed axons get on track

Article Abstract:

Bonkowsky and colleagues have shown that the choice of pathways for growth cones in Drosophila melanogaster is controlled by Derailed (Dr1), a receptor tyrosine kinase. It is likely that Dr1 causes growth cones to be repelled from the wrong pathways. They have shown that Dr1 is normally expressed on axons following the anterior commissure, but not on those taking the posterior route.

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A new code for axons

Article Abstract:

Issues are presented concerning the methods which are used by growing axons to develop along specific pathways. The utilization of Slit-to-Robo signalling by a large number of different species is discussed.

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Frazzled precision guides axons

Article Abstract:

Issues are presented concerning the cues which guide the direction of axion and dendrite growth in developing embryos. The growth of axons in the fruitfly Drosophila melanogaster is discussed.

Embryology, Animal embryology, Dendrites

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