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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Ephrin signalling controls brain size regulating apoptosis of neural progenitors

Article Abstract:

The ephrin-A/EphA receptor signalling plays a key role in controlling the size of the mouse cerebral cortex by regulating cortical progenitor cell apoptosis. The results indicate that ephrin/Eph signalling is identified as a physiological trigger for apoptosis that can alter brain size and shape by regulating the number of neural progenitors.

Author: Depaepe, Vanessa, Suarez-Gonzalez, Nathalie, Dufour, Audrey, Passante, Lara, Gorski, Jessica A., Jones, Kevin R., Ledent, Catherine, Vanderhaeghen, Pierre
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
United Kingdom, Mice, Cerebral cortex, House mouse

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Divide and conquer

Article Abstract:

The mitochondria in mammalian cells fragment into smaller pieces when the cells die by the process of apoptosis. It is concluded that the release of mitochondrial proteins stimulates mitochondrial division and it is indicated that mitochondrial fragmentation is caspase-independent which means that is an early event in the apoptotic programme.

Author: Hengartner, Michael
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
United States, Mitochondria, Mammals, Cell research, Cytological research

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Suppression of CED-3-independent apoptosis by mitochondrial beta NAC in Caenorhabditis elegans

Article Abstract:

Caenorhabditis elegans inhibitor of cell death-1 (ICD-1) is necessary and sufficient to prevent apoptosis. Cells must integrate developmental information with regulatory inputs to control the switch between repressing and activating apoptosis.

Author: Bloss, Tim A., Witze, Eric S., Rothman, Joel H.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
Care and treatment, Usage, Caenorhabditis elegans

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Subjects list: Research, Genetic aspects, Apoptosis
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