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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Ipr1 gene mediates innate immunity to tuberculosis

Article Abstract:

A new genetic locus on mouse chromosome 1, designated as sst1(super susceptibility to tuberculosis 1) is found out. The study show that this locus mediates innate immunity in sst1congenic mouse strains and identify a candidate gene, Intracellular pathogen resistance 1(Ipr1), within the sst1 locus.

Author: Hui Pan; Bo-Shiun Yan; Rojas, Mauricio, Shebzukhov, Yuriy V.; Zhou, Hongwei, Kobzik, Lester; Higgins, Darren E., Daly, Mark J.; Bloom, Barry R., Kramnik, Igor
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
United States, Tuberculosis, Drug resistance in microorganisms, Microbial drug resistance

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The large-conductance Ca (super 2+) -activated K (super +) channel is essential for innate immunity

Article Abstract:

Neutrophil leukocytes have a pivotal function in innate immunity. K (super +) crosses the membrane through large -conductance ca (super 2+) -activated K (super +) channels. The channels were opened by the combination of membrane depolarization and elevated ca (super 2+) concentration.

Author: Ahluwalia, Jatinder, Tinker, Anderw, Clapp, Lucie H., Duchen, Michael R., Abramov, Andrey Y., Pope, Simon, Nobles, Muriel, Segal, Anthony W.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Neutrophils, Leukocytes, White blood cells

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The equilibria that allow bacterial persistence in human hosts

Article Abstract:

A new equilibria model that explains the common features of microbial persistence in their human hosts is reported. The model could be used to understand the direction of virulence as the context of human ecology changes.

Author: Blaser, Martin J., Kirschner, Denise
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
Models, Host-bacteria relationships, Virulence (Microbiology)

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Subjects list: Research, Immunity, Immunity (Physiology)
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