Loading the type III cannon
Article Abstract:
The loading mechanism of the bacterial type III secretion system that injects certain bacterial proteins into adjacent host cells is presented. The protein selected by the secretion machinery often resemble the host's own proteins, so they could switch off defensive systems and turn the cells into puppets of a bacterial master.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Antibiotic stops 'ping-pong' match
Article Abstract:
Pathogenic bacteria have developed strains that are resistant to almost all antibiotics in use today. Researchers show that platensimycin inhibits the catalytic cycle by binding to the acyl-enzyme intermediate, preventing the addition of malonyl-ACP substrate-blocking fatty-acid biosynthesis and so acting as an antibiotic.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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