Modulation of GABA(sub A) receptors by tyrosine phosphorylation

Article Abstract:

Tyrosine phosphorylation is inhibited by mutations in tyrosine residues in the intracellular region of the gamma-2-L subunit of gamma-aminobutyric acid type-A (GABA-A), similar to regulation of GABA-A in neuronal cultures, indicating that the modulation of tyrosine kinase probably affects neuronal excitation. Phosphorylation of tyrosine accelerates the whole-cell current stimulated by GABA and GABA-A receptors are crucial in acting as intermediaries in fast synaptic inhibition.

Observations, Protein tyrosine kinase, Protein-tyrosine kinase, Neurons, GABA, GABA receptors

---

Bidirectional control of CNS capillary diameter by pericytes

Article Abstract:

A study was conducted to show that pericytes which are apposed to central nervous system (CNS) capillaries and contain contractile proteins could control capillary diameter in whole retina and cerebellar slices. The results suggest that pericytes are probably modulators of blood flow in response to changes in neural activity, which might contribute to functional imaging signals and to CNS vascular disease.

Science & research, Central nervous system, Neurotransmitters, Capillaries

---

Similar abstracts:

• Abstracts: Stimulation of protein tyrosine phosphorylation by the B-lymphocyte antigen receptor. Tolerance: a second mechanism
• Abstracts: Stimulation of protein tyrosine phosphorylation by the B-lymphocyte antigen receptor. part 2 V(D)J recombinase induction in splenic B lymphocytes is inhibited by antigen-receptor signalling
• Abstracts: Elongation factor-1-alpha gene determines susceptibility to transformation. A kinase from fission yeast responsible for blocking mitosis in S phase
• Abstracts: Identification of a galaxy responsible for a high-redshift Lyman-alpha absorption system. The O/C abundance ratio in absorbing gas clouds at high redshift
• Abstracts: Production of sperm reduces nematode lifespan. A message from the gonads. Regulation of lifespan by sensory perception in Caenorhabditis elegans

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.