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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Myelin-like sheaths in copepod axons

Article Abstract:

It appears that nerve fibres of many copepods are designed for rapid signalling. They have well-developed myelin-like sheaths, which reduce a copepod's reaction time to predatory attack and may therefore be vital for the survival of the large copepod populations found in dangerous oceanic ecosystems. In copepods with the myelin-like sheaths, almost all axons of both sensory and motor nerves of the first antenna are ensheathed. Copepod myelin has concentrically arranged layers of membrane around the axon.

Author: Weatherby, Tina M., Davis, April D., Hartline, Daniel K., Lenz, Petra H.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
Physiological aspects, Copepoda, Copepods

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NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia

Article Abstract:

N-methyl-D-aspartate (NMDA) glutamate receptors mediate Ca(super 2+) accumulation in central myelin in response to chemical ischaemia in vitro. The Ca(super 2+) increase mediated in large part by activation of myelinic NMDA receptors suggest a mechanism of axo-myelinic signalling, representing a potentially important therapeutic target in multiple sclerosis and aspects of ischaemic brain injury in which demyelination is a prominent feature.

Author: L. Zhang, Micu, I., Woulfe, J., Zamponi, G.W., Q.Jiang, X. Yin W, Wang, Coderre, D., Trapp, B.D., Stys, P.K., Ridsdale, A., McRory, J.E., Rehak, R.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
Care and treatment, Risk factors, Cerebral ischemia, Methyl aspartate, N-methyl-D-aspartate

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Assault on the guardian

Article Abstract:

The contribution of autoimmunity to a protein known as [alpha]-B-crystallin (CRYAB) on inflammatory injury of the central nervous system, such as multiple sclerosis (MS), is described. It is shown that polymorphisms in the promoter genes encoding CRYAB might affect disease severity and a suspected mediator of damage in MS can use CRYAS as a substrate, offering another way in which inflammation might reduce the protein's availability.

Author: Ransohoff, Richard M.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
Autoimmunity, Immunoproteins

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Subjects list: Research, Myelin sheath, Health aspects, United States, Causes of, Multiple sclerosis
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