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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I

Article Abstract:

A study to show that Sgo1 recruits to centromeres a specific form of protein phosphatase 2A (PP2A) in both fission and budding yeast is presented. The data are consistent with the notion that efficient cleavage of Rec8 requires phosphorylation of cohesion and that this is blocked by PP2A at meiosis I centromeres.

Author: Galova, Marta, Nasmyth, Kim, Mechtler, Karl, Petronczki, Mark, Gregan, Juraj, Ogris, Egon, Katou, Yuki, Shirahige, Katsuhiko, Katis, Vittorio L., Mori, Saori, Itoh, Takehiko, Riedel, Christian G., Helmhart, Wolfgang, Mudrak, Ingrid, Pelletier, Laurence, Cetin, Bulent, Buchholz, Frank
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
United States, Meiosis, Cohesion, Cohesion (Materials), Centromeres

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Cohesin mediates transcriptional insulation by CCCTC-binding factor

Article Abstract:

The article discusses association of the cohesin-binding sites in human genome with the CCCTC-binding factor (CTCF), protein required for the process of transcriptional insulation. The findings prove that cohesin mainly helps in mediating transcriptional insulation by the CCCTC-binding factor.

Author: Peters, Jan-Michael, Koch, Birgit, Nakao, Mitsuyoshi, Aburatani, Hiroyuki, Bando, Masashige, Shirahige, Katsuhiko, Itoh, Takehiko, Wendt, Kerstin S., Yoshida, Keisuke, Schirghuber, Erika, Tsutsumi, Shuichi, Nagae, Genta, Ishihara, Ko, Mishiro, Tsuyoshi, Yahata, Kazuhide, Imamoto, Fumio, Imamoto, Naoko, Maeshima, Kazuhiro
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2008
Genetic regulation, Genetic transcription, Transcription (Genetics), DNA binding proteins, Zinc finger proteins, Human genome

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S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex

Article Abstract:

The checkpoint regulatory mechanism plays an important role in maintaining the integrity of the genome. The checkpoint regulatory proteins Tof1 and Mrc1 are explained to interact directly with the DNA replication machinery.

Author: Ashikari, Toshihiko, Katou, Yuki, Bando, Masashige, Noguchi, Hideki, Tanaka, Hirokazu, Kanoh, Yutaka, Sugimoto, Katsnori, Shirahige, Katsuhiko
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
Analysis, Proteins, Genomes, DNA replication

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