Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1 beta

Article Abstract:

Interleukin-1 is an essential mediator of inflammatory conditions which consists of two agonists namely IL-1a and IL-1beta and one antagonist, IL-1ra. The IL-1beta binds to s-IL1R which has a crystal structure that contains three immunoglobulin-like domains. The binding of IL-1a or IL-1beta to IL1R is an initial step in interleukin-1 signal transduction which can be a useful target for the development of new medicines when this interaction has been blocked.

Analysis, Interleukin-1

---

A blueprint for life

Article Abstract:

The common bacterium Escherichia coli and its bacterial viruses are well used in science research because they have ideal pathogenic, and nutritional characteristics. However, the functions of up to 40% of an estimated 4,288 genes in E. coli have not yet been established. Scientists need to launch a cooperative international research strategy to ascertain the bacterium's genetic makeup.

International aspects, Genetic aspects, Escherichia coli, Genetic research

---

Similar abstracts:

• Abstracts: High-resolution structure of a DNA helix forming (C.G)*G base triplets. Surface-promoted replication and exponential amplification of DNA analogues
• Abstracts: Seamounts make earthquakes. Probe of a plate interior: Earth science. Earthquakes with gold linings
• Abstracts: The role of the anterior prefrontal cortex in human cognition. Reward expectancy in primate prefrontal neurons
• Abstracts: In defence of the Department of Energy. Problems with stockpile stewardship. Rethinking on weapons clean-up
• Abstracts: Energy and trace-gas fluxes across a soil pH boundary in the Arctic. CO2 fluctuation at high altitudes

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.