Decreased dietary copper impairs vascular function
Article Abstract:
Copper deficiency in living systems has a negative impact on vascular function due to impaired interaction between endothelium-derived relaxing factor (EDRF) and the smooth muscle cells of large blood vessels and microvasculature. Nitric oxide (NO), on being released from the endothelial cells which line blood vessel walls, passes through membranes toward target enzymes embedded inside cells. It relaxes the smooth muscle cells and dilates the blood vessel, causing a drop in blood pressure. NO has one unpaired electron and behaves like a free radical to display the behavior of a biological emissary.
Publication Name: Nutrition Reviews
Subject: Food/cooking/nutrition
ISSN: 0029-6643
Year: 1993
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Biological chemistry of thiols in the vasculature and in vascular-related disease
Article Abstract:
The chemistry of amino thiols and their roles in normal and diseased physiology of blood vessels are discussed. The amino thiols have an SH group and consist of homocysteine, cysteine, and glutathione. Their oxidation properties and reactivity under different conditions is described. Each amino thiol is described in detail, with reference to its role in the function of platelets, smooth muscles, blood vessel lining, and atherosclerosis.
Publication Name: Nutrition Reviews
Subject: Food/cooking/nutrition
ISSN: 0029-6643
Year: 1996
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Is low copper status immunosuppressive?
Article Abstract:
The reduction of the trace mineral copper in T cells suggests a compromise in resistance to infectious disease. Animal and cellular experiments show an adequate amount of copper is responsible for the development of and function of cells that make up the immune system. The exact role of copper needs further study.
Publication Name: Nutrition Reviews
Subject: Food/cooking/nutrition
ISSN: 0029-6643
Year: 1998
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