Distinction between preclinical Alzheimer's disease and depression

Article Abstract:

Distinguishing between depression and preclinical Alzheimer's disease (AD) is discussed relative to a prospective observational cohort study at an outpatient memory clinic of a university-affiliated hospital. Depression was found to be common in preclinical AD patients. Those with preclinical AD can be differentiated from those with depression-related cognitive impairment by severity of memory loss and age. Preclinical AD is often accompanied by depression and research investigating preclinical AD should not exclude those with depression a priori

Author: Visser, Pieter Jelle, Verhey, Frans R.J., Ponds, Rudolf W.H.M., Kester, Arnold, Jolles, Jellemer
United States, Diagnosis, Statistics, Depression, Mental, Depression (Mood disorder), Dementia, Alzheimer's disease, Depression in old age, Geriatric depression

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Change in sensory functioning predicts change in cognitive functioning: results from a 6-year follow-up in the Maastricht Aging Study

Article Abstract:

A study on the relation between sensory functioning and cognition among older Dutch adults who had participated in Maastricht Aging Study is presented. The sensory functions examined are visual and auditory senses and its effect on cognitive performance is analyzed at baseline and 6 years follow-up. The results indicate a strong relation between sensory and cognitive functioning.

Author: Ponds, Rudolf W.H.M., Valentijn, Susanne A.M., Van Boxtel, Martin P.J., Van Hooren, Susan A.H., Bosna, Hans, Beckers, Henry J.M., Jolles, Jelle
Netherlands, Science & research, Cognition disorders in old age, Geriatric cognitive disorders, Sensory disorders

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An operation under general anesthesia as a risk factor for age-related cognitive decline: results from a large cross-sectional population study

Article Abstract:

Research shows no correlation between the use of general anesthesia and cognitive impairment. In studies of elderly surgical patients, no evidence was found that anesthesia brought on or accelerated age-related cognitive decline. While anesthesia usage increased the number of patients' health-related complaints, memory complaints were not statistically significant.

Author: Jolles, Jellemer, Van Boxtel, Martin P.J., Houx, Peter J., Dijkstra, Jeanette B.
Psychological aspects, Health aspects, Surgery, Anesthesia, Cognition

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Subjects list: Research
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