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Apparent stabilizing selection and the maintenance of neutral genetic variation

Article Abstract:

Pleiotropic models of quantitative genetic variation presents scenarios where genes responsible for the heritability of the character are not eliminated by selection on the character itself. One of these models, the Hill-Keightley, attempts to show that the selection is a result of the unconditionally deleterious effects of the genes that cause heritability. An analysis of the model indicates that selection is compatible with neutral variation of the genes affecting the trait.

Author: Wagner, Gunter P.
Publisher: Genetics Society of America
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1996
Natural selection, Quantitative genetics

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Analysis of conditional genetic effects and variance components in developmental genetics

Article Abstract:

A study was conducted to examine quantitative traits with time-dependent measures using a genetic model with additive-dominance effects and genotype and environment interactions. Statistical methods for analyzing conditional genetic effects and conditional genetic variance components were proposed. Conditional variances were estimated by minimum norm quadratic unbiased estimation method.

Author: Zhu, Jun
Publisher: Genetics Society of America
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1995
Developmental genetics

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