MEI-1/MEI-2 katanin-like microtubule severing activity is required for Caenorhabditis elegans meiosis

Article Abstract:

MEI-1/MEI-2 katanin-like microtubule severing activity is necessary for meiosis in Caenorhabditis elegans. The C. elegans meiotic spindle is distinct morphologically from the first mitotic spindle. Nevertheless the structures form in the same cytoplasm. Cloning and molecular characterization of mei-2, a gene first identified as an mei-(ct46gf) supressor, are described. Coexpression of MEI-1 and MEI-2 in HeLa cells results in disassembly of microtubules. MEI-1 is an ATPase associated with various cellular activities (AAA).

Canada, Microtubules, Meiosis

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Acetylation regulates subcellular localization of the Wnt signaling nuclear effector POP-1

Article Abstract:

Acetylation has been found to regulate localization within the cell of the Wnt signaling nuclear effector POP-1, the Caenorhabditis elegans lymp hoid enhancer factor/T-cell factor (L EF/TCF) homolog. The mechanism is upping nuclear import and blocking nuclear export. Three lysines acetylated in vivo have been identified. They are needed for POP-1 nuclear localization and biological activity in C. elegans embryogenesis.

Science & research, Reports, Embryology, Animal embryology, Cell nuclei, Cell nucleus

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MAD2B is an inhibitor of the anaphase-promoting complex

Article Abstract:

MAD2B has been found to be an inhibitor of the anaphase-promoting complex.

Statistical Data Included, Messenger RNA, Anaphase

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