Identification of new loci involved in adhesion of Listeria monocytogenes to eukaryotic cells

Article Abstract:

Researchers describe new loci involved in cell adhesion in Listeria monocytogenes in addition to the well-known genes inlA and inlB. Insertional mutagenesis was used to detect these genes. A mutant that was most defective in cell adhesion had insertions at five different sites.

Cell adhesion

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SvpA, a novel surface virulence-associated protein required for intracellular survival of Listeria monocytogenes

Article Abstract:

Research has been conducted on the 64 kDa secreted protein of Listeria monocytogenes. The role of this protein has been investigated via constructing an allelic mutant of the gene that encodes this protein and the results indicate that this protein is required for the intracellular survival and virulence of L. monocytogenes.

Statistical Data Included, Analysis, Gene mutations, Gene mutation, Cells (Biology), Proteins, Gene expression, Cells, Microbiological research

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Modification of the signal sequence cleavage site of listeriolysin O does not affect protein secretion but impairs the virulence of Listeria monocytogenes

Article Abstract:

Research has been conducted on virulence factor listeriolysin O secreted by Listeria monocytogenes. The authors suggest that N-terminal residues of listeriolysin O participate directly in phagosomal escape and bacterial infection.

Science & research, Research, Microbiology, Secretion, Bacterial proteins, Lysine

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