Molecular mechanism of AHSP-mediated stabilization of alpha-hemoglobin

Article Abstract:

An integrated approach combining nuclear magnetic resonance, X-ray crystallography, and biochemical and biophysical analyses is used to investigate the molecular mechanism by which the alpha-hemoglobin stabilizing protein (AHSP) stabilizes alpha-hemoglobin (alpha-Hb). Results define a mechanistic pathway describing how AHSP protects against cytotoxicity caused by alpha-Hb.

Proteins, Nuclear magnetic resonance

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Cellular and molecular signatures of muscle regeneration: Current concepts and controversies in adult myogenesis

Article Abstract:

The historical basis and evidence for the identification of satellite cells as adult muscle stem cells is described and contributions of other cells to adult myogenesis is evaluated. Data regarding the origins, genetic markers, and molecular regulation of satellite cells is normal, diseased, and aged muscles are summarized.

United States, Muscles, Muscle cells, Myogenesis, Muscle regeneration, Stem cell research

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