Stem cells: units of development, units of regeneration, and units in evolution

Article Abstract:

Evolution of development is discussed with emphasis on stem cells, particularly the hematopoietic ones (HSCs), the best-characterized of the stem cells. It is proposed that stem cell-based organogenesis and regeneration, stem cell mobility, and the coevolution of polymorphic histocompatibility that limits stem cells to self or close relatives are interrelated themes and are coselected in an evolutionary sense.

United States, Natural selection, Cell cycle, Cell differentiation, Neurons, Cytology, Hematopoietic stem cells, Developmental neurology, Protochordates, Germ cells

---

Genomic imprinting, mammalian evolution, and the mystery of egg-laying mammals

Article Abstract:

Mammalian evolution, genomic imprinting, and egg-laying mammals are discussed in this minireview. The mechanism of genomic imprinting, an unusal type of gene regulation in eutherians, can be better understood through greater understanding of the cis-regulatory regions. Differential expression of imprinted genes seems to regulate the asymmetry between parental contributions to the developing fetus.

United Kingdom, Australia, Physiological aspects, Natural history, Embryology, Animal embryology, Cytogenetics, Marsupialia, Marsupials, Animal reproduction, Platypus, Anteaters, Genomic imprinting

---

Plasticity of adult stem cells

Article Abstract:

Adult mammalian stem cells can be capable of differentiating across tissue lineage boundaries, and as such may represent novel, accessible, and very versatile effectors of therapeutic tissue regeneration. The role of adult stem cells in tissue regeneration and studies suggesting lineage plasticity of adult stem cell populations is briefly reviewed.

Science & research

Similar abstracts:

• Abstracts: Structural analysis of Bacillus megaterium KM spore peptidoglycan and its dynamics during germination. Complete spore-cortex hydrolysis during germination of Bacillus subtilis 168 requires SleB and YpeB
• Abstracts: A 22 kb DNA sequence in the cspB-glpPFKD region at 75 degrees on the Bacillus subtilis chromosome. Chaperone-like activities of the CsaA protein of Bacillus subtilis
• Abstracts: MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. The hallmarks of cancer
• Abstracts: Twisted perspective: New insights into extracellular modulation of BMP signaling during development. Signaling - 2000 and beyond
• Abstracts: Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI. Flipping the switch: the structural basis for signaling through the CRIB motif

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.