Study of biochemical pathways and enzymes involved in pyrene degradation by Mycobacterium sp. strain KMS

Article Abstract:

The pyrene degradation pathway used by Mycobacterium sp. strain KMS and its capacity is determined by isolating and identifying the metabolites, and also the proteomic profile of Mycobacterium sp. strain KMS is obtained. All the enzymes required during the initial steps of pyrene degradation are identified by proteomic study and a pyrene degradation pathway for Mycobacterium sp. strain KMS is proposed and confirmed.

Utah, Physiological aspects, Benzopyrene, High performance liquid chromatography, Chemical properties

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Distribution of the coenzymeM pathway of epoxide matabolism among ethene- and vinyl chloride-degrading Mycobacterium strains

Article Abstract:

The distribution of the epoxyalkanecoenzyme M transferase in ten mycobacterial strains is presented. Results indicate that 6 strains can be isolated on vinyl chloride and 4 strains from that of ethene. All of the ten species possess enzyme activity and its cognate genes. Data reveal that in the former, the enzyme is encoded on linear megaplasmids.

United States, Environmental aspects, Genetic aspects, Microbial metabolism, Bacteria, Aerobic, Aerobic bacteria, Enzyme synthesis

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Initial reaction(s) in biotransformation of CL-20 is catalyzed by salicylate 1-monooxugenase from Pseudonomonas sp. Strain ATCC 29352

Article Abstract:

The CL-20 is an extremely energetic multicyclic nitramine compound, which has very high explosive characteristics. The Salicylate 1-monooxygenase and flavin adenine dinucleotide comprises of the enzyme from Psudonomonas sp. Strain ATCC 295352 and also has the capacity to catalyze the various biochemical reactions.

Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Nonnarcotic Analgesic Preparations, Pseudomonas, Oxidases, Microbiology, Properties, Salicylates, Aminosalicylate sodium

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