Synaptonemal complexes from DNase-treated rat pachytene chromosomes contain (GT)sub n and LINE/SINE sequences

Article Abstract:

Cloning and sequencing of synaptonemal complexes from digested rat pachytene chromosomes revealed (GT)sub n repeats and 'long' and 'short' interspersed repetitive element (LINE/SINE) sequences. These repeats ranged between 100 to 500 base pairs long. Hybridization studies revealed that the SC-associated LINE fragments were significantly different from genomic LINE fragments. Tandem repetition of the (GT)sub n sequences suggested that the SC-associated DNA was selectively enriched with these sequences. Localization of the (GT)sub n and LINE sequences was also attempted, but was unsuccessful.

Rats

---

A short chromosomal region with major roles in yeast chromosome III meiotic disjunction, recombination and double strand breaks

Article Abstract:

Addition of plasmids containing a fragment from the middle of Saccharomyces cerevisiae chromosome III right arm cause a twofoldenhancement of cis acting nondisjunction of chromosome III in the host yeast. The plasmid undergoes integration with the chromosome of the host yeast spontaneously in both normal and nondisjunctive meioses although more readily in the latter. The fragment from chromosome III apparently encompasses a 'hot spot' for recombination as proven by a strong signal for double strand breaks induced by meiosis.

---

Commitment to meiosis in Saccharomyces cerevisiae: involvement of the SPO14 gene

Article Abstract:

The SPO14 gene of Saccharomyces cerevisiae was mapped and sequenced. Results show that it follows Mendelian genetics and is localized to the right arm of chromosome XI. Mutants with the spo14 trait were not irreversibly committed to meiosis at the late stages of meiosis when wild-type cells have already been fully committed. Thus, SPO14 gene is thought to code for a factor involved in the coordinated induction of events in late meiosis. This coordinate induction could be the basis for the commitment phenomenon.

Similar abstracts:

• Abstracts: Use of cosmid-derived and chromosome-specific canine microsatellites. FISH mapping and identification of canine chromosomes
• Abstracts: Mutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII
• Abstracts: Streptomyces genomes: circular genetic maps from the linear chromosomes. part 2 Characterization of the gene for factor C, an extracellular signal protein involved in morphological differentiation of Streptomyces griseus
• Abstracts: Oligomeric tubulin in large transporting complex is transported via kinesin in squid giant axons. The 4-angstrom X-ray structure of a tubulin-stathmin-like domain complex
• Abstracts: The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis. The serpin alpha1-proteinase inhibitor is a critical substrate for gelatinase B/MMP-9 in vivo

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.