Telomere length homeostatis is achieved via a switch between telomerase-extendible and -nonextendible states

Article Abstract:

A study to measure telomere elongation at nucleotide resolution in Saccharomyces cerevisiae though the cell cycle varies between a few to more than 100 nucleotides and is independent of telomere length is presented. Thus, it is shown that telomere length homeostatis is achieved via a switch between telomerase-extendible and -nonextendible states by taking a molecular snapshot of a single round of telomere replication.

Analysis, Cell cycle

---

Telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae

Article Abstract:

A complete analysis of telomerase, a ribonucleoprotein enzyme that elongates telomeres to counteract telomere shortening is presented. Results prove that the telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae.

Genetic aspects, Mutation (Biology), Mutation, Telomerase

---

A class of membrane proteins shaping the tubular endoplasmic reticulum

Article Abstract:

The identification of membrane proteins involved in endoplasmic reticulum (ER) network formation is discussed. The major components shaping the tubular ER are the reticulons and the interacting protein DP1/Yop 1p.

Massachusetts, Usage, Endoplasmic reticulum, Membrane proteins, Immunoblotting

Similar abstracts:

• Abstracts: Retrotransposons and regulatory suites. Adding to the ends: what makes telomerase processive and how important is it?
• Abstracts: Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome
• Abstracts: Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27. A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
• Abstracts: Telomere elongation is under the control of the RNAi-based mechanism in the Drosophila germline. Drosophila atm/telomere fusion is required for telomeric localization of HP1 and telomere position effect
• Abstracts: Relevance of the endosymbiosis of Blochmannia floridanus and carpenter ants at different stages of the life cycle of the host

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.