Yeast TAF(sub II)145 functions as a core promoter selectivity factor, not a general coactivator

Article Abstract:

A differential display was employed to determine the small subset of yeast genes which needs yTAF(sub II)145 for in vivo transcription. Promoter-mapping analysis indicate that the core promoter is the gene region that is dependent on yTAF(sub II)145, and not the upstream activating sequence with activator-binding sites. Results also show that the core promoter recognition and selection function of yTAF(sub II)145 does not require upstream activators.

Research, Genetic aspects, Promoters (Genetics), Genetic transcription, Transcription (Genetics), Yeast, Yeast (Food product)

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Compartmentalization of eukaryotic gene expression: Causes and effects

Article Abstract:

Eukaryotic structural gene expression involves gene transcription and transport of processed mRNA to the cytoplasm. There are indications that the eukaryotic nucleus may be functionally compartmentalized, and a model whereby the expression of genes directs the reorganization of nuclear components is supported.

Observations, Eukaryotic cells, Cells (Biology), Eukaryotes, Gene expression

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