Multiple roles for PrP in the prion diseases
Article Abstract:
The isoform of the prion protein PrP(super C), PrP(super Sc), is found to be a major part of a damaged brain suffering from transmissible spongiform encephalopathies (TSE) or prion diseases. Since mice without PrP(super C) are not affected by TSE, PrP protein is concluded to cause the disease. Studies on mice reveal that postsynaptic PrP is found to have a possible role in the proper performance of inhibitory synapses. There is also a possibility that synaptic regulation by PrP sustains a lasting life for Purkinje cells which are largely damaged in affected specimens.
Publication Name: Trends in Neurosciences
Subject: Psychology and mental health
ISSN: 0166-2236
Year: 1996
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Hotels vie for Manila, resorts
Article Abstract:
The increase in tourism has prompted hotel operators to build more hotels in the Philippines. ITT Sheraton has agreed to 15 hotel management contracts and Wingate has agreed to build 30 more hotels. 10.5% of capital investment and 8.7% of Gross National Product (GDP) of the Philippines come from tourism. The tourism department has undertaken some initiatives to increase the number of visitors and change the image of tourism in Philippines.
Publication Name: International Business Asia
Subject: Business, international
ISSN: 1324-5414
Year: 1997
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Menu development
Article Abstract:
A report concerning the menu development of independent restaurants and eating out chains is presented. Issues discussed include frequency of eating out, organic food, vegetarianism, trade response, consumer response and research methodology.
Publication Name: Leisure Intelligence (Mintel)
Subject: Business, international
ISSN:
Year: 2000
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