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Chronic, programmed polypeptide delivery from an implanted, multireservoir microchip device

Article Abstract:

The controlled pulsatlle release of the polypeptide leuprolide from microchip implants over six months in dogs is described. Each microchip contains an array of discrete reservoir from which dose delivery can be controlled by telemetry.

Author: Prescott, James H., Lipka, Sara, Baldwin, Samuel, Sheppard, Norman F., Jr., Maloney, John M., Coppeta, Jonathan, Yomtov, Barry, Staples, Mark A., Santini, John T., Jr.
Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2006
Integrated & Hybrid Circuits, Research, Usage, Semiconductor chips, Technology application, Polypeptides, Protein research, Telemetry, Leuprolide, Standard IC

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Controlled-release microchip

Article Abstract:

Researchers from the Massachusetts Institute of Technology developed an automated method of delivery of insulin using a controlled-release microchip.

Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 1999
Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Antidiabetic Preparations, Silicon Chips, Brief Article, Hypoglycemic agents

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Hotwiring biosensors

Article Abstract:

Chemical and biological sensors could be developed by fitting integrated circuits with silicon nanowires containing biomolecules.

Publisher: Nature Publishing Co.
Publication Name: Nature Biotechnology
Subject: Business
ISSN: 1087-0156
Year: 2001
Biochemistry, Research and Development in the Physical, Engineering, and Life Sciences, Illustration

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Subjects list: United States, Integrated circuits
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