Replicative adenoviruses for cancer therapy

Article Abstract:

Major progress is being seen in replication-competent virus engineering for the treatment of cancer. Adenovirus, a human virus that is mildly pathogenic, reproduces rapidly in epithelial cells.

Immunology

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Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays

Article Abstract:

Human cancers result from a combination of discrete mutations and chromosomal alterations. A key event in the evolution of epithelial and meschymal tumors is the loss of heterozygosity (LOH) of chromosomal regionsbearing mutated tumor suppression genes.

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Cell factories for fighting cancer

Article Abstract:

Two groups offer new strategies for sustained delivery of protein-based angiogenesis inhibitors. These inhibitors can prevent experimental growth of tumors and metastasis.

Cellular Biology, Cytology

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