Multivalent avimer proteins evolved by exon shuffling of a family of human receptor domains

Article Abstract:

A class of binding proteins, called avimers is developed to overcome the limitations of antibodies and other immunoglobulin-based therapeutic proteins. Linking multiple independent binding domains creates avidity and results in improved affinity and specificity compared with conventional single-epitope binding proteins.

Properties, Binding proteins

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Ordered surface carbons distinguish antifreeze proteins and their ice-binding regions

Article Abstract:

A generic ice-binding model is formulated and incorporated it into a physicochemical pattern-recognition algorithm. Results show that the algorithm is used to identify a novel antifreeze protein (AFP) from winter rye, and the antifreeze activity of this protein was subsequently confirmed.

All Other Miscellaneous Chemical Product and Preparation Manufacturing, Chemical preparations, not elsewhere classified, Antifreeze, Chemistry, Physical and theoretical, Physical chemistry, Anti-freeze solutions

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Isjolation of high-affinity ligand-binding proteins by periplasmic expression with cytometric screening (PECS)

Article Abstract:

Ligand-binding proteins can be isolated from diverse libraries utilizing periplasmic expression with cytometric screening (PECS)

Research & development outlays, Protein, Proteins, Human nutrition

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