The imitation game: a computational chemical approach to recognizing life

Article Abstract:

An approach to the recognition of living artificial chemical system based on chemical cells as a Gedankenexperiment that exploits a cellular imitation game is proposed. The separation of physical embodiment and ability, as in the original Turning test for artificial intelligence (AI), must be preserved to develop a Gedankenexperiment version of an idealized cellular imitation game.

Life, Origin of life, Artificial cells, Turing test

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Computational discovery of gene modules and regulatory networks

Article Abstract:

Research discusses an algorithm that enables finding regulatory networks of the genetic regulatory modules, which combine information on genome-wide location and expression data sets. Results demonstrate a genome-wide regulatory network in Saccharomyces cerevisiae using binding data for 106 transcription factors.

Analysis, Evaluation, Genetic regulation, Genomes, Genetic algorithms, Genes

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Ensemble modeling for analysis of cell signaling dynamics

Article Abstract:

The article discusses the application of ensemble modeling with proper experimental study for the analysis of complex cell signaling dynamics. The technique is found to be extremely efficient for explaining the characterized cellular circuits in microorganisms.

Usage, Bayesian statistical decision theory, Bayesian analysis, Systems biology

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