High-resolution optical imaging from trajectory time distributions

Article Abstract:

A systematic investigation of the effects of the threshold that separates fluorescent bursts from background signals and of two or more probes visiting the vesicles simultaneously is performed. Experimental results along with simulations indicate the capability of trajectory time distribution optical microscopy (TTDOM) to provide the size and shape of objects and information on probe-vesicle binding.

Other Lighting Equipment Manufacturing, Lighting equipment, not elsewhere classified, Marine Beacons, Beacons & Marker Lighting, Beacons, Gas vesicles, Structure

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Chiral memory on tradition between the B2 and B4 phases in an achiral banana-shaped molecular system

Article Abstract:

The correlation between chirality of the B2 and B4 phases are examined by measuring the circular dichroism in the classic bent-core molecule. By incorporating the optical microscopic observations with the CD measurements, it is found that once the chiral domains are formed in the B4 phase they are conserved thereafter on successive transformation between the B2 and B4 phases.

Analysis, Chirality, Circular dichroism

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Probing structural dynamics of individual calmodulin: Peptide complexes in hydrogels by single-molecule confocal microscopy

Article Abstract:

An environment-sensitive probe, Nile Red, tagged to a designed model peptide, is used to probe the structural changes and dynamics of single calmodulin (CaM):peptide complexes. Findings shows that on the 10-100-mu(s) time scale the CaM:peptide complex is tumbling within the hydrogel matrix.

Peptides, Calmodulin, Chemical properties, Structural dynamics

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