Chemical analysis in small domains: introduction

Article Abstract:

Developments in scanning tunneling and atomic force microscopies are making it possible to undertake research in fields of analytical chemistry in which chemical information is required in increasingly smaller dimensions. Chemical analysis in small domains will also become more significant as a result of the search for advances in bioengineering, materials science and the biological sciences.

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Near-field scanning optical microscopy

Article Abstract:

Near-field scanning optical microscopy (NSOM) has become a suitable method for obtaining new information about sample properties at the nanometric scale. NSOM is proving to be a very flexible technology, and its single molecule fluorescence detection limits and spectroscopic abilities are very valuable when linked with the high spatial resolution.

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Chemical and biochemical analysis using scanning force microscopy

Article Abstract:

A discussion of developments in the use of scanning force microscopy (SFM) as a technique for analysis is presented. SFM has made it possible to achieve very high levels of sample interrogation and manipulation. This will in turn create new opportunities in the design of nanoscale landscapes.

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