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Long-term Outcomes of Persons With Lyme Disease

Article Abstract:

Lyme disease may have no significant long-term complications, especially in people who have taken antibiotics. In a study of 678 patients with suspected Lyme disease, 64% were definitely diagnosed with the disease. Over 85% had been treated with antibiotics. Almost 70% said they had pain, fatigue, or difficulty with daily activities. However, the rate of these problems was no greater in those with Lyme disease than in those without Lyme disease.

Author: Seltzer, Elyse G., Gerber, Michael A., Cartter, Matthew L., Freudigman, Kimberly, Shapiro, Eugene D.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000

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A controlled trial of antimicrobial prophylaxis for Lyme disease after deer-tick bites

Article Abstract:

Giving antibiotics to individuals who have been bitten by a deer tick may not be necessary, even in areas with a high prevalence of Lyme disease. Deer ticks carry the bacterium Borrelia (B.) burgdorferi, which causes Lyme disease. Proper care and possible treatment for deer-tick bites in areas where Lyme disease is prevalent. In a one-year study of 387 people who had been bitten by deer ticks, 205 were given the antibiotic amoxicillin and 182 were given a placebo, or inactive substance. Some brought the ticks with them, and of 344 ticks analyzed, 15% were infected with B. burgdorferi. Only two patients on taking placebo developed symptoms of B. burgdorferi infection, and none of those on amoxicillin developed the infection. The risk of infection did not differ significantly between the group taking amoxicillin and the group taking placebo.

Author: Gerber, Michael A., Shapiro, Eugene D., Holabird, Nancy B., Feder, Henry M., Jr., Persing, David H., Rys, Paul N., Berg, Anne T., Bell, Gillian L.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1992
Usage, Prevention, Amoxicillin

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Lyme disease in children in southeastern Connecticut

Article Abstract:

Children in the early stages of Lyme disease who are treated with conventional antibiotics can be cured of the disease. This was demonstrated in a study of 201 children living in a part of Connecticut where Lyme disease is widespread. About 90% of the children had one or more erythema migrans rashes, which are typical of Lyme disease. They were all treated with oral antibiotics such as amoxicillin, penicillin, doxycycline, erythromycin or ceftriaxone for 2 to 4 weeks. Within one week, the children were asymptomatic and up to 24 months later, none had Lyme disease.

Author: Gerber, Michael A., Shapiro, Eugene D., Bell, Gillian L., Burke, Georgine S., Parcells, Valerie J.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
Health aspects, Children, Connecticut, Child health

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Subjects list: Prognosis, Lyme disease
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