A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines

Article Abstract:

Studies were conducted to highlight the importance of carbonyl groups in formaldehyde-treated vaccines and to explain the adverse effects of formaldehyde vaccines in measles and respiratory syncytial virus (RSV) infections. The data from the studies show that the induction of carbonyl groups on vaccine antigens by formalin treatment might profoundly affect immunogenicity, changing the balance between protective and deleterious immune responses.

All Other Basic Organic Chemical Manufacturing, Industrial organic chemicals, not elsewhere classified, Formaldehyde, Health aspects, Causes of, Allergy, Carbonyl compounds, Allergic reaction

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Introducing new vaccines into developing countries: Obstacles, opportunities and complexities

Article Abstract:

Infectious diseases are the major causes of poverty and economic underdevelopment in developing countries and development and deployment of new vaccines in these regions has become the major priority. Details of the opportunities, and complexities for the vaccine introduction in the developing countries are discussed.

Product introduction, New Products/Services, Drugs, Developing Countries, Economic aspects, Political aspects, Biological products industry, New products, New technique

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Measles vaccines: a positive step toward eradicating a negative strand

Article Abstract:

Research presented concerns the development of a measles DNA vaccine to aid in the elimination of measles worldwide. A study of the efficacy of a DNA vaccine encoding the measles fusion or hemagglutinin proteins is discussed.

Research, Measles vaccine, Measles vaccines, Measles virus, DNA vaccines

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