ACVBP versus CHOP plus radiotherapy for localized aggressive lymphoma

Article Abstract:

A randomized trial comparing chemoradiotherapy with chemotherapy is conducted to determine the optimal therapy for noneldery persons with low-risk localized lymphoma. The results obtained from the trial conclude that in patients less than 61 years of age, chemotherapy with three cycles of doxorubicin, cyclophosphamide, vindesine, bleomycin, and prednisone (ACVBP) followed by sequential consolidation is superior to three cycles of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) plus radiotherapy for the treatment of low-risk localized lymphoma.

Radiotherapy, Lymphomas

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Antibacterial prophylaxis after chemotherapy for solid tumors and lymphomas

Article Abstract:

A random trial was performed whereby patients receiving chemotherapy for solid tumor or lymphoma were administered levofloxacin or matching placebo during the expected neutropenic period. Results revealed that the prophylactic use of levofloxacin minimized the occurrence of fever, infection and hospitalization among these patients.

New England States, Drug therapy, Bacterial infections, Dosage and administration, New England, Neutropenia, Prophylaxis, Levofloxacin

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Palifermin for oral mucositis after intensive therapy for hemotologic cancers

Article Abstract:

The ability of palifermin is tested to decrease oral mucosal injury induced by cytotoxic therapy was tested. It was found that palifermin reduced the duration and severity of oral mucositis after intensive chemotherapy and radiotherapy for hematologic cancers.

Risk factors, Oral mucosa, Blood diseases, Hematologic diseases

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