Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration

Article Abstract:

A large, national multicenter study is used to assess whether the genes CFH and LOC387715 are associated with age-related macular degeneration (AMD) and related visual loss. The results show that common polymorphisms in the genes CFH and LOC387715 are independently related to AMD progression after adjustment for other known AMD risk factors.

Development and progression, Genetic aspects, Single nucleotide polymorphisms, Clinical report

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Age-related macular degeneration is the leading cause of blindness...

Article Abstract:

The prevalence and distribution of age-related macular degeneration (AMD) in the United States by age, race/ ethnicity, and gender is estimated. The study concluded that age-related macular degeneration affects more than 1.75 million individuals in the United States.

United States, Causes of, Risk factors, Blindness

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