Benign cutaneous polyarteritis nodosa in children below 10 years of age - a clinical experience

Article Abstract:

Benign cutaneous polyarteritis nodosa (BCPAN) can occur even in young children. In this rare disease, the lining of blood vessels in the skin, muscles, and joints develops nodular inflammations that can block blood flow, resulting in tissue death. It is believed to be triggered by a hypersensitive reaction. It is chronic, but can be controlled, and is benign in that it is not life-threatening. Between 1980 and 1991 ten children under ten years of age were diagnosed with BCPAN at a Chandigarh, India hospital. All had fevers and skin lesions, eight had gangrene of the fingers or toes, and seven had painful, swollen joints. Seven had lost fingers or toes to gangrene. All of these children had come for treatment late, one month to four years after symptom onset. Microscopic analysis of biopsies of the skin lesions revealed the vascular inflammation. All have responded to treatment with corticosteroids or cytotoxic drugs.

Pediatric diseases, Children, Diseases, Arteritis

---

Polyarteritis nodosa with angioedema

Article Abstract:

Polyarteritis nodosa (PAN) may be rare in children but detectable in biopsied tissue containing dead fibrous tissue and inflamed muscle arteries. A 12-year-old boy was diagnosed with PAN after failed antibiotic therapy to treat sore throat, fever, and a neck mass. The diagnosis of PAN was confirmed by results of a skin biopsy from a foot, which showed inflamed muscle arteries and dead tissue. There may be a connection between group A streptococcal infection and PAN in children. Treatment with corticosteroids and cyclophosphamide has decreased the death rate from PAN to under 20%.

Periarteritis nodosa, Polyarteritis nodosa

---

Pneumomediastinum in dermatomyositis: association with cutaneous vasculopathy

Article Abstract:

Patients with dermatomyositis have an increased risk of pneumomediastinum, which occurs when air enters the space surrounding the heart. Dermatomyositis is an inflammatory disease of muscles that also affects the skin.

Causes of, Complications and side effects, Dermatomyositis, Pneumomediastinum

Similar abstracts:

• Abstracts: The neurological illness of Eugene O'Neill -- a clinicopathological report. Memory dysfunction
• Abstracts: Antiviral resistance in influenza viruses-implications for management and pandemic response
• Abstracts: Diagnosis and treatment of cutaneous facial sinus tracts of dental origin. Dental treatment of patients with long QT syndrome
• Abstracts: Pregnancy potential of human oocytes - the effect of cryopreservation. Bit player or powerhouse? China and stem-cell research
• Abstracts: CMV-antigenemia in peripheral blood for the diagnosis of CMV disease in HIV-infected patients. Influence of HIV epidemic on the incidence of Kaposi's sarcoma in Zambian children

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.