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Central diabetes insipidus: a complication of ventriculoperitoneal shunt malfunction during pregnancy

Article Abstract:

Shunts for brain and spinal fluid may be at higher risk of becoming blocked during pregnancy, and permanent diabetes insipidus may be a resulting complication. Diabetes insipidus is caused by a lack of pituitary antidiuretic hormone output and results in dehydration from excessive urination. A 31-year-old 26 weeks' pregnant woman was unresponsive after two months of headaches, vomiting, and progressive loss of consciousness. Two years earlier, a brain and spinal fluid shunt was placed after an illness. She was rehydrated and the shunt, which was found to be blocked, was flushed. Diabetes insipidus was suspected, and the patient responded to antidiuretic hormone treatment. The fetus resumed growth until 34 weeks' gestation, and cesarean delivery resulted in a healthy infant. Diabetes insipidus continued.

Author: Goolsby, Lynn, Harlass, Frederick
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1996
Complications and side effects, Diabetes insipidus, Peritoneovenous shunts, Peritoneovenous shunt

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Decreased plasma adiponectin concentrations in women with gestational diabetes mellitus

Article Abstract:

The plasma adiponectin levels in women are analyzed with gestational diabetes mellitus because gestational diabetes is associated with obesity and decreased insulin sensitivity. The results show that decreased plasma adiponectin levels were found in women with gestational diabetes mellitus compared with unaffected women.

Author: Worda, Christof, Leipold, Heinz, Gruber, Christian, Kautzky-Willer, Alexandra, Knofler, Martin, Bancher-Todesca, Dagmar
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2004
United States, Observations, Fat cells, Adipocytes

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Influence of maternal and fetal glucokinase mutations in gestational diabetes

Article Abstract:

A mutation in the gene for the enzyme glucokinase may cause a mild form of diabetes during pregnancy. Because the mutation might be inherited by the baby, the baby might be affected also. A women with the mutation had two children, one of whom inherited the mutation and had an extremely low birth weight.

Author: Spyer, Ghislaine, Hattersley, Andrew T., Sykes, Jean E., Sturley, Rachel H., MacLeod, Kenneth M.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2001
Health aspects, Gene mutations, Gene mutation

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Subjects list: Causes of, Diabetes in pregnancy, Gestational diabetes
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