Dietary protein and blood pressure

Article Abstract:

More research is needed on the link between protein intake and blood pressure. Several observational studies have found that people with high-protein diets seemed to have lower blood pressure. Clinical trials have failed to confirm this, but many of these trials were not designed primarily to study the relationship between protein intake and blood pressure. Many nutritionists believe that high-protein diets can damage the kidney. It is also unclear how high-protein diets would reduce blood pressure. Presumably, the effect would arise from increased blood levels of amino acids, which would affect blood vessels or the region of the brain that affects blood pressure. But amino acid metabolism is tightly controlled and is not affected substantially by diet. Large, well-designed studies are needed to evaluate the link between protein intake and hypertension, which affects an estimated 50 million Americans.

Nutritional aspects, Proteins in human nutrition, Dietary protein

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Effect of reduced dietary sodium on blood pressure: a meta-analysis of randomized controlled trials

Article Abstract:

It may be unwise to recommend dietary sodium restriction until further research confirms that the treatment is safe and effective. Researchers used meta-analysis to evaluate 56 clinical trials of the effect of sodium reduction on blood pressure. The trials covered 1,131 people with hypertension and 2,374 people with normal blood pressure. A reduction in daily sodium intake of approximately 2,000 milligrams reduced blood pressure by 3.7/0.9 in those with hypertension and by 1/0.1 in those with normal blood pressure. Reduction in blood pressure was greatest in hypertensive patients 45 or older but was insignificant in younger patients. Reductions in blood pressure were also insignificant in the people with normal blood pressure. Many of the studies that showed greater reductions in blood pressure were flawed. There is evidence that a low-sodium diet can actually be harmful.

Salt-free diet, Sodium restricted diet

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Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol: A randomized controlled trial

Article Abstract:

A randomized controlled trial is used to evaluate the efficacy of a comprehensive pharmacy care program to improve medication adherence and its associated effects on blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C). The results have shown that pharmacy care program led to increase in medication adherence, medication persistence and clinically meaningful reductions in BP, but the discontinuation of this program was associated with decreased medication adherence and persistence.

Science & research, Research, Evaluation, Low density lipoproteins, Clinical report

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