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Epstein-Barr virus in action in vivo

Article Abstract:

New research strengthens the link between the Epstein-Barr virus and cancer affecting the B cells of the immune system. The virus has been implicated in Burkitt's lymphoma, Hodgkin's disease and lymphoproliferative disease in transplant recipients who must take immunosuppressive drugs. When B cells are infected by the virus, they produce a protein called LMP1. This protein in turn transforms the cells into cancer. A 1998 study found LMP1 in tumor samples from transplant recipients, who also tested positive for the virus.

Author: Rickinson, A.B.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1998
Editorial, Lymphoproliferative disorders, Immunoproliferative disorders, Lymphomas

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Serologic markers of Epstein-Barr virus infection and nasopharyngeal carcinoma in Taiwanese men

Article Abstract:

The Epstein-Barr virus may cause some cases of nose cancer, according to a study of 9,699 men who were tested for antibodies against the virus and then followed for up to 15 years. Those who had antibodies to the virus in their blood at the start of the study were 33 times more likely to develop nose cancer than those who had no viral antibodies.

Author: Chen, Chien-Jen, Chien, Yin-Chu, Chen, Jen-Yang, Liu, Mei-Ying, Yang, Hwai-I., Hsu, Mow-Ming, Yang, Czau-Siung
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
Risk factors, Nose cancer

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Epstein-Barr virus infection

Article Abstract:

The Epstein-Barr virus infecting over 90 percent of human population causes heterophile-positive infectious mononucleosis and is also detected in nasopharyngeal carcinoma, Hodgkin's disease, T-cell lymphoma, and AIDS patients. Vaccination against Epstein-Barr virus infection has shown initial success in children.

Author: Cohen, Jeffrey, I.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
United States, Evaluation, Children, Vaccination of children, Vaccination, Virus diseases, Disease transmission, Mononucleosis, Infectious mononucleosis

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Subjects list: Health aspects, Causes of, Epstein-Barr virus
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