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Estrogen-receptor status and outcomes of modern chemotherapy for patients with node-positive breast cancer

Article Abstract:

A study was conducted to compare differences in benefits from adjuvant chemotherapy achieved by patients with estrogen-receptor (ER), ER-negative versus ER-positive tumors. It was found that among patients with node-positive tumors, ER-negative breast cancer, biweekly doxorubicin/cyclophosphamide plus paclitaxel lowers the rate of recurrence and death by more than 50% in comparison with low-dose cyclophosphamide, doxorubicin, and fluorouracil.

Author: Goldstein, Lori J., Martino, Silvana, Norton, Larry, Muss, Hyman B., Cirrincione, Constance, Citron, Marc L., Perez, Edith A., Hudis, Clifford, Berry, Donald A., Henderson, Craig I., Budman, Daniel R.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
Patient outcomes, Drug therapy, Estrogen, Estrogen receptors

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Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer

Article Abstract:

A study was conducted to compare the benefits and toxic effects of adjuvant chemotraphy among breast cancer patients in age groups of 50 years of younger, 51 to 64 years, and 65 years or older. It was revealed that age alone should not be a contraindication to the use of optimal chemotraphy regiments in older women who are in good general health.

Author: Weiss, Raymond B., Norton, Larry, Muss, Hyman B., Budman, Daniel, Wood, William C., Cirrincione, Constance, Berry, Donald, Hudis, Clifford, Wheeler, Judith, Woolf, Susan, Henderson, I Craig, Cohen, Harvey
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
Diagnosis, Young women, Aged women, Elderly women

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Preoperative chemotherapy for breast cancer

Article Abstract:

A study assessed the benefits of a treatment, preoperative chemotherapy in breast cancer patients. Results revealed that it was recommended for patients who had inoperable breast cancer as it offered an option of reducing the tumor size leading to less scarring at the time of surgery.

Author: Hudis, Clifford, Modi, Shanu
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
Complications and side effects

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Subjects list: Health aspects, Care and treatment, United States, Breast cancer, Cancer, Chemotherapy
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