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Eyeing a new route along an old pathway

Article Abstract:

Issues related to diagnosing glaucoma are examined, focusing on research that identifies the role of the endothelial leukocyte-adhesion molecule-1 (ELAM-1) in the disease. Topics include implication for pharmacological and genetic therapy for the disease, and the use of ELAM-1 for finding diagnostic markers of glaucoma.

Author: Tomarev, Stanislav I.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
United States, Eye diseases, Glaucoma

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Death, destruction, danger and dendritic cells

Article Abstract:

Dendritic cells can be activated by necrotic tissue inside the body. This supports the hypothesis that the immune system reacts to conditions that could be dangerous. However, the mechanism by which necrotic tissue activates dendritic cells is unclear.

Author: Austyn, Jonathan M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 1999
Physiological aspects, Antigen presenting cells, Necrosis

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