Impact of laboratory-initiated reporting of CD4+ T lymphocytes on U.S. AIDS surveillance

Article Abstract:

States that report CD4+ T cell counts appear to report AIDS cases at an earlier stage of infection. The case definition of AIDS was changed in 1993 to include CD4+ T cell counts less than 200. Many states began reporting CD4+ counts in preparation for the changed definition. A survey of states found that states that reported CD4+ counts also reported more AIDS cases compared to states that did not report CD4+ counts. States with CD4+ reporting also reported AIDS cases at an earlier stage when the disease is amenable to treatment.

Measurement, AIDS (Disease), Disease reporting, CD4 lymphocytes

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Is there really a heterosexual AIDS epidemic in the United States? Findings from a multisite validation study, 1992-1995

Article Abstract:

Researchers conducted a study to verify the mode of exposure to the HIV among individuals who obtained the disease through heterosexual intercourse. Heterosexual risk was validated in 82% of the cases. Among the 415 men, 52% were classified, 44% has sex with other men, 28% were injection drug users, 22% had a heterosexual risk, and 6% had other exposures. Among the 219 women, 62% were classified, 60% had a heterosexual risk, 35% were injection drug users, and 4% had infection through blood transfusion.

Case studies, Women, Diseases, Homosexuality, HIV infection in women

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Unreported AIDS-defining opportunistic illnesses in persons reported with HIV-related severe immunosuppression

Article Abstract:

A study of 3,289 patients diagnosed with AIDS after the CDC changed the case definition in 1993 found that 10% had an unreported opportunistic infection. The case definition of AIDS was changed to include severe immunosuppression in the absence of an opportunistic infection.

Statistical Data Included, Complications and side effects, Statistics, Opportunistic infections

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