Molecular genotyping of fetal platelet antigens with uncultured amniocytes

Article Abstract:

A molecular test of fetal platelet type may eliminate the need for fetal blood sampling to determine the risk of the fetus having a life-threatening low platelet count because of platelet incompatibility with its mother. Researchers developed a reverse dot blot technique to type the five platelet antigen groups of a fetus and mother and father whose last infant died as a result of platelet incompatibility. The parents were found to have incompatible platelet types, so the fetus had a 50% risk of having platelets incompatible with the mother. Analysis of amniotic fluid obtained from amniocentesis found the fetus to have compatible platelet antigens to the mother, so he was not at risk. Fetal blood sampling, a somewhat risky procedure, was not necessary, nor were blood treatments.

Methods, Diagnosis, Polymerase chain reaction, Thrombocytopenia, Prenatal diagnosis

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Training in chorionic villus sampling: Limited experience for US fellows

Article Abstract:

The training availability, methods and plans for practice of invasive procedures for maternal fetal medicine (MFM) fellows are assessed. Studies reveal that the number of training centers for MFM fellows in chorionic villus sampling (CVS) and the number of procedures performed in the United States is limited.

Science & research, Research, Analysis, Pregnancy, Complications of, Pregnancy complications, Chorionic villus sampling

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A new device for measuring intrauterine temperature

Article Abstract:

The Softrans Temp intrauterine pressure-temperature catheter appears to be useful in monitoring the temperature inside the uterus. This catheter has a thermistor sensor in the tip and is available from from Graphics Control Co., Buffalo, NY.

Evaluation, Product information, Measurement, Body temperature, Medical thermometers, Graphics Control Co.

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