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Power failure, liver failure

Article Abstract:

A case of fatal food poisoning illustrates one of the mechanisms of liver failure. A 17-year-old boy died of liver failure four days after eating rewarmed spaghetti. Analysis of samples of the spaghetti and the boy's liver revealed the presence of the bacterium Bacillus cereus. This bacterium secretes a toxin that can damage mitochondria. The mitochondria can no longer provide energy to cells and the cells die. There have been reports of similar fatalities in Japan and Thailand, since the bacterium favors cooked rice.

Author: Schafer, Daniel F., Sorrell, Michael F.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1997
Editorial, Liver failure, Mitochondria

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Body-mass index and symptoms of gastroesophageal reflux in women

Article Abstract:

The association between body mass index (BMI) and symptoms of gastroesophageal reflux diseases explored by determining the relative risks among a broader range of categories of BMI and among persons with various degrees of frequency, severity, and duration of symptoms. BMI is found to be associated with symptoms of gastroesophageal reflux disease in both normal-weight and overweight women, where even moderate weight gain in persons of normal weight might cause or exacerbate symptoms of reflux.

Author: Kelly, Ciaran P., Fuchs, Charles S., Jacobson, Brian C., Somers, Samuel C., Camargo, Carlos
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
New England States, Health aspects, Measurement, Overweight persons, New England, Body mass index, Gastroesophageal reflux, Clinical report

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Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A

Article Abstract:

Some people who become infected with Clostridium difficile will have a mild form of the disease because their immune system produces antibodies against the bacterial toxin that causes diarrhea. In a study of 271 hospital patients, 37 were infected with Clostridium difficile at the time of admission and 47 became infected while hospitalized. Thirty-seven had no symptoms. Those with high blood levels of IgG antibody against Clostridium toxin were less likely to develop diarrhea.

Author: Kyne, Lorraine, Warny, Michel, Qamar, Amir, Kelly, Ciaran P.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
Clostridium infections

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Subjects list: Causes of, Physiological aspects, Bacterial toxins
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