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Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins

Article Abstract:

The large veins leading from the lungs to the heart may be a source of abnormal electrical activity in patients with atrial fibrillation. Atrial fibrillation is a common heart arrhythmia. Researchers used catheters to place small electrodes in the heart and pulmonary veins of 45 patients with atrial fibrillation. These electrodes can detect abnormal electrical activity prior to the onset of the arrhythmia and can also pinpoint its source. Ninety-four percent of the abnormal activity occurred in the pulmonary veins. The patients were treated with radio-frequency ablation, which eliminated atrial fibrillation in 62%.

Author: Garrigue, Stephane, Hocini, Meleze, Haissaguerre, Michel, Clementy, Jacques, Jais, Pierre, Takahashi, Atsushi, Shah, Dipen C., Quiniou, Gilles, Le Mouroux, Alain, Le Metayer, Philippe
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1998
Physiological aspects, Heart, Electric properties, Pulmonary veins, Pulmonary vein

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Catheter ablation for atrial fibrillation in congestive heart failure

Article Abstract:

A study is conducted to evaluate the effect of catheter ablation for atrial fibrillation on left ventricular function in patients with heart failure. The conclusion states that restoration and maintenance of sinus rhythm by catheter ablation without the use of drugs in patients with congestive heart failure improve cardiac function, symptoms, exercise capacity and quality of life.

Author: Garrigue, Stephane, Li-Fern Hsu, Hocini, Meleze, Rotter, Martin, Scavee, Christophe, Bordachar, Pierre, Haissaguerre, Michel, Clementy, Jacques, Pasquie, Jean-Luc, Yakahashi, Yoshihide, Sacher, Federic, Senders, Prashanthan, Jais, Pierre
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Science & research, England, Research, Risk factors, Influence, Catheter ablation

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Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay

Article Abstract:

Atriobiventricular pacemakers may benefit patients with heart failure and an intraventricular conduction delay, according to a study of 48 patients. Atriobiventricular pacemakers have one electrode in the upper part of the heart and two in the lower part of the heart.

Author: Cazeau, Serge, Leclercq, Christophe, Lavergne, Thomas, Walker, Stuart, Varma, Chetan, Linde, Cecilia, Garrigue, Stephane, Kappenberger, Lukas, Haywood, Guy A., Santini, Massimo, Bailleul, Christophe, Daubert, Jean-Claude
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2001
Care and treatment, Evaluation, Arrhythmia, Pacemaker, Artificial (Heart), Pacemakers

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Subjects list: Atrial fibrillation, Heart failure
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