Abstracts - faqs.org

Abstracts

Health

Search abstracts:
Abstracts » Health

The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of antiogenic growth factors

Article Abstract:

Research has been conducted on the prototypical morphogen Sonic hedgehog which regulates epithelial and mesenchymal interactions during embryonic development. Results indicate that the hedgehog-signaling pathway is present in the cardiovascular tissues of the adults and can be activated in vivo.

Author: Silver, Marcy, Kearney, Marianne, Isner, Jeffrey M., Pola, Roberto, Ling, Leona E., Corbley, Michael J., Pepinski, R. Blake, Shapiro, Renee, Taylor, Frederick R., Baker, Darren P., Asahara, Takayuki
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2001
United States, Statistical Data Included, Analysis, Physiological aspects, Genetic aspects, Medical research, Epithelial cells, Morphogenesis, Epithelium, Angiogenin

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Favorable effect of VEGF gene transfer on ischemic peripheral neuropathy

Article Abstract:

Researchers were able to reverse the symptoms of hindlimb ischemia in rabbits by intramuscular injections of DNA coding for vascular endothelial growth factor. This growth factor is involved in angiogenesis, which could create collateral blood vessels in patients with ischemia.

Author: Schratzberger, Peter, Schratzberger, Gabrielle, Silver, Marcy, Curry, Cynthia, Kearney, Marianne, Magner, Meredith, Alroy, Joseph, Adelman, Lester S., Weinberg, David H., Ropper, Allan H., Isner, Jeffrey M.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2000
Health aspects, Peripheral nerve diseases, Peripheral nervous system diseases

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Sonic hedgehog myocardial gene therapy: Tissue repair through transient reconstitution of embryonic signaling

Article Abstract:

Sonic hedgehog (Shh) is a crucial regulator of organ development during embryogenesis. The intramyocardial gene transfer of naked DNA is investigated to see whether encoding human Shh could promote a favorable effect on recovery from acute and chronic myocardial ischemia.

Author: Silver, Marcy, Curry, Cynthia, Kearney, Marianne, Pola, Roberto, Porter, Jeffery A., Kusano, Kengo F., Murayama, Toshinori, Kawamoto, Atsuhiko, Iwakura, Atsushi, Shintani, Satoshi, Ii, Masaaki, Asai, Jun, Tkebuchava, Tengiz, Thorne, Tina, Takenaka, Hideya, Aikawa, Ryuichi, Goukassian, David, Samson, Patrick von, Hamada, Hiromichi, Yoon, Young-sup, Eaton, Elizabeth, Ma, Hong, Heyd, Lindsay, Munger, William, Kishore, Raj, Losordo, Douglas W.
Publisher: Nature America, Inc.
Publication Name: Nature Medicine
Subject: Health
ISSN: 1078-8956
Year: 2005
Science & research, Research, Gene therapy, Genetic transformation

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Growth factors, Care and treatment, Ischemia
Similar abstracts:
  • Abstracts: Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy
  • Abstracts: Treatment of chronic plaque psoriasis by selective targeting of memory effector T lymphocytes. Cyclosporine for plaque-type psoriasis: results of a multidose, double-blind trial
  • Abstracts: This working life: an interview with George Brumwell. The working wounded: arthritis & rheumatism. This working life: ladder safety
  • Abstracts: The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy
  • Abstracts: Diverse compounds mimic Alzheimer disease - causing mutations by augmenting Abeta42 production. A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.