The ubiquitin system

Article Abstract:

Research discusses the role of ubiquitin in the cellular protein degradation process and delineates the ubiquitin-proteolytic pathway. Results reveal that an ATP-dependent proteolysis factor 1 is the ubiquitin and it is an integral part of the proteolysis system. The pathway is identified as an N-end-rule pathway mediated by degradation signals, N-degrons.

Research, Metabolic regulation, Proteolysis

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Linking ubiquitin, parkin and synphilin-1

Article Abstract:

Research has been conducted on the Parkinson disease characterized by the presence of Lewy bodies-intracytoplasmic protein accumulation. The molecular link between the formation of these bodies, ubiquitin, parkin and synphilin-1 has been investigated and the results are discussed.

Causes of, Medical research, Parkinson's disease, Parkinson disease, Molecules

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Inhibition of virus-induced neuronal apoptosis by Bax

Article Abstract:

Inhibition by the Bax protein of virus-induced neuronal apoptosis has been studied in mice infected with Sindbis virus. Cell-specific factors appear to determine the anti-apoptotic vs pro-apoptotic function of Bax.

Japan, Statistical Data Included, Usage, Cell death, Mice, Mice (Rodents), Viruses, Neurons

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