Treatment of men with paraphilia

Article Abstract:

More research is needed on effective treatments for deviant sexual disorders, a condition also called paraphilia. People with this condition are usually imprisoned, but drug treatment may allow them to remain in the community. A 1998 study found that a drug called triptorelin reduces testosterone production and suppresses abnormal sexual thoughts and desires. Other possible treatments include anti-androgens such as flutamide and cyproterone acetate and medroxyprogesterone. The US Supreme Court has upheld the civil detention of these patients until they can be properly treated.

Editorial

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Immediate hormonal therapy compared with observation after radical prostatectomy and pelvic lymphadenopathy in men with node-positive prostate cancer

Article Abstract:

Therapy to suppress male sex hormones appears to be beneficial for men with prostate cancer who have had their prostate removed. Sex hormones can often stimulate cancers. Researchers randomly assigned 98 men with prostate cancer who had their prostate removed to have anti-androgen therapy or no further treatment. At the last follow-up, 77% of the men who received anti-androgen therapy were alive and well compared to 18% of the men who did not. Men who received anti-androgen therapy were also less likely to have a relapse.

Care and treatment, Prostate cancer

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Treatment of men with paraphilia with a long-acting analogue of gonadotropin-releasing hormone

Article Abstract:

Drugs that mimic the action of gonadotropin-releasing hormone may be effective in the treatment of deviant sexual behavior, or paraphilia, in men. These drugs can lower the amount of testosterone in the body. One such drug called triptorelin was given by monthly injections to 30 men with long-term paraphilia in addition to psychotherapy. All the men had fewer deviant sexual fantasies and desires while on the drug and a drop in the number of abnormal behaviors. Their testosterone levels also dropped significantly.

Health aspects, Gonadotropin releasing hormone, Gonadorelin

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