Molecular characterization of alpha1- and alpha2-adrenoceptors

Article Abstract:

The six alpha-adrenoceptors that were divided into alpha1-adrenoceptors and alpha2-adrenoceptors featured various subtypes with differing binding properties. Molecular clones of these alpha-adrenoceptors failed to provide results that distinctly characterized their function as that of an alpha1- or an alpha2-adrenoceptor. However, the application of tests with proper receptor-channel mechanisms could significantly improve the characterization of alpha-adrenoceptor function.

Cover Story, Cloning, Epinephrine, Structure-activity relationships (Pharmacology), Adrenergic receptors, Structure-activity relationship (Pharmacology)

---

alpha2-adrenoceptors take centre stage at Nashville meeting

Article Abstract:

A symposium held on Oct. 25-27, 1995, in Nashville, TN, focused on recent advances in alpha2-adrenoceptors research. Pharmacological data from experimental systems provided evidence supporting the important role of alpha2- and other adrenoceptor subtypes in the management of a variety of cellular and molecular functions in relation to the treatment of different diseases such as bipolar depression, analgesia and glaucoma.

Conferences, meetings and seminars, Reports, Nashville, Tennessee, Drug receptors, Adrenergic alpha blockers, Adrenergic alpha-antagonists

---

Life on the edg

Article Abstract:

Research demonstrates that some of the edg family of G-protein-coupled receptors are high-affinity sphingosine-1-phosphate or lysophosphatidic acid receptors. Data are presented on their role as a group as lysolipid phosphate receptors.

United States, Analysis, Brief Article, Physiological aspects, Cellular signal transduction, Lipid research, Neurotransmitter receptors, Sphingosine

Similar abstracts:

• Abstracts: Pharmacological prospects for alpha2-adrenoceptor antagonist therapy. Application of in situ microdialysis to measure metabolic and vascular responses in adipose tissue
• Abstracts: Schizophrenia, the dopamine hypothesis and alpha(sub)2-adrenoceptor antagonists. Endocannabinoids and multiple sclerosis: a blessing from the 'inner bliss'?
• Abstracts: Movement seen in cosmetics harmonization. ICI Acquires Unilever's Speciality Chemicals Business. Martha Matilda Harper's formula for success
• Abstracts: Frequency use of botanicals. Fragrance stability in three cosmetic applications
• Abstracts: Caprolactam: Neues Verfahren GERMANY: ETHYLENE INVESTMENT BY ERDOLCHEMIE. GERMANY: DOW CONSIDERING NEW CRACKER

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.