Microsatellite markers for standardized genetic management of captive colonies of rhesus macaques (Macaca mulatta)

Article Abstract:

A standardized genetic management strategy is essential for the efficient organization of breeding colonies sponsored by the National Center for Research Resources (NCRR), whose common mission is to breed rhesus macaques for use as animal models in biomedical research. A core panel, which comprises four multiplex PCR assays, generates a large amount of genotypic information that is suitable for easy computer entry, storage, and retrieval, and its use is not limited to any automated genotyping platforms.

Public affairs, Sexual behavior, Social aspects, Analysis, Animal radio tracking, Animal breeding

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Mitochondrial DNA variation in Chinese and Indian rhesus macaques (Macaca mulatta)

Article Abstract:

Rhesus macaques (Macaca mulatta) are used more extensively than any other primate species as animal models for the study of human disease. The results suggest that Indian and Chinese rhesus macaques were reproductively isolated during most of the Pleistocene, during which time Indian rhesus macaques experienced a severe genetic bottleneck, and the some gene flow westward into India was subsequently reestablished.

China, India, Evaluation, Genetic variation

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Prevalence of antibodies to selected viruses in a long-term closed breeding colony of rhesus macaques (Macaca mulatta) in Brazil

Article Abstract:

A serologic survey was conducted to determine the prevalence of antibodies to selected viruses. The results provide data, useful for the development and implementation of strategies in order to destroy the endemic viruses.

Brazil, Animal experimentation, Viral antibodies, Antibodies

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