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"Smart" genes use many cues to set cell fate

Article Abstract:

Developmental biologist Eric Davidson and Chiou-Hwa Yuh present evidence suggesting that a gene in the sea urchin Strongylocentrotus purpuratus contains mechanisms that enable it to pick up various chemical signals which determine the fate of the cell in which the gene resides.

Author: Roush, Wade
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
Genetic regulation

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Defining the first steps on the path toward cell specialization

Article Abstract:

A research teams led by molecular geneticist Patrick Straigier and developmental biologist Richard Losick have identified a single protein, SpoIIE, which enables a bacterium to produce progeny that are genetically identical, yet which develop different functions.

Author: Roush, Wade
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1995
Cell division, Straiger, Patrick, Losick, Richard

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Protein motors may drive cells on route to specialization

Article Abstract:

Research evidence suggests that cellular specialization relies on motor proteins that carry a unknown regulatory protein from mother to daughter cell that works with a protein called Ash 1p to prevent mating-type switching in the daughter cell.

Author: Roush, Wade
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996

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Subjects list: Research, Cell differentiation, Cellular control mechanisms, Cell regulation
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