Progressive trends in the prevalence of benzodiazepine prescribing in older people in Ontario, Canada

Article Abstract:

Research indicates that Canadian physicians are reducing the role of benzodiazepine therapy for patients 65 years of age and older. The annual number of benzodiazepine prescriptions declined consistently between 1993 and 1998, and short-acting drugs, rather than long-acting ones, were dispensed more often than before. Another noticeable trend was the replacement of benzodiazepines with antidepressants.

Ontario, Statistical Data Included, Prevention, Benzodiazepines, Benzodiazepine abuse

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Drug-induced lithium toxicity in the elderly: a population-based study

Article Abstract:

The association between the risk of hospitalization for lithium toxicity and the use of diuretics, angiotensin-converting enzyme (ACE) inhibitors, and nonsteroidal anti-inflammatory drugs (NSAIDs) in the elderly are examined. It was found that the use of loop diuretics or ACE inhibitors significantly increases the risk of hospitalization for lithium toxicity, particularly in naive recipients.

United States, Health aspects, Lithium, Lithium drugs

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Age- and gender-related use of low-dose drug therapy: the need to manufacture low-dose therapy and evaluate the minimum effective dose

Article Abstract:

Research concerning the prevalence of low-dose drug therapy in older adults, especially those of advanced age and women, is discussed. Results indicate that the prescribed dosages of thiazide diuretic to older adults do not match manufactured dosages and trials are needed to determine the minimum effective dose of beta-blockers.

Care and treatment, Drugs, Adrenergic beta blockers, Adrenergic beta-antagonists, Drug administration and dosage, Thiazides

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