A most interesting factor

Article Abstract:

Research into the working of the signalling molecule macrophage migration inhibitory factor (MIF) in the immune system is discussed. MIF has now been shown to interact inside cells with Jab 1, an activator of gene expression.

Macrophages, Immune system

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Lipid rafts and insulin action

Article Abstract:

Issues are presented concerning the pathways which allow insulin to function in the body as a stimulant for glucose removal by fat and muscle cells. The mechanism of insulin function is discussed.

Diabetes, Diabetes mellitus, Insulin, Insulin structure-activity relationships

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Mal (MyD88-adaptor-like) is required for Toll-like receptor-4 signal transduction

Article Abstract:

The way that the immune system recognizes pathogens is examined in detail. The mechanics of signal transduction is studied, with an assessment of the role of receptors.

Analysis, Immunological research, Immunologic research

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