Label-free immunodetection with CMOS-compatible semiconducting nanowires
Article Abstract:
An approach is described that uses complementary metal oxide semiconductor (CMOS) field effect transistor compatible technology and show the specific label-free detection of below 100 femtamolar concentrations of antibodies as well as real-time monitoring of the cellular immune response. The method has eliminated the necessity of hybrid methods and has enabled system-scale integration of the sensors with signal processing and information systems.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
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Origins of chemical biodefense
Article Abstract:
The atomic-resolution crystal structure of C3, as well as that of an inactivated fragment, C3c are presented. From the structure of C3, it is apparent how this large multi-domain protein evolved from a series of simpler building blocks into a tightly regulated killing machine.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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